What is the location of the Pope's official residence?

The Pope's official residence is located in Vatican City, an independent city-state enclaved within Rome. Vatican City serves not only as the spiritual and administrative center of the Roman Catholic Church but also as the residence of the Pope. The significance of this location is profound, as Vatican City is home to many important religious sites, including St. Peter's Basilica and the Vatican Museums, which hold immense historical and cultural value.

The distinction of Vatican City as the Pope's residence is crucial; while it is situated within the city of Rome, it functions as its own sovereign entity with unique governance and religious authority. This separation emphasizes its importance not just as a physical location but as a central spiritual hub for millions of Catholics worldwide. Other locations like Florence and Genoa do not hold any official connection to the papacy and are primarily known for their own historical and cultural significance.